Since Hydra now exists as an evil, terrorist organization (Thanks, Hydra Bob), Blind Al sends Bob and Deadpool to stop them from releasing a deadly biological toxin on the city of Cincinnati. Our heroes swoop in and succeed in saving the day, stopping Taskmaster and her Hydra goons before the Liquid X bombs can be detonated. Their victory is short lived, however, as the bombs go off anyway and Ohioans start melting in the street. Al accuses Bob of orchestrating this mayhem as part of his grand Hydra scheme and Deadpool and Bob saunter off into the sunset as public enemy #1 (and 2).