Riots break out around the world immediately following an assassination attempt on Fury. Tony Stark explains how only an "image projected onto a force field" was "killed", and the 4 assassins left alone so they could report back to whoever hired them. Other agents are being killed around the world, and the leaders of the riots exhibit no emotions, as if they were zombies. Aboard the Heli-Carrier, a meeting of the board of directors is interrupted by a transmission from "Supremus", who orders SHIELD to be disbanded in the wake of Fury's death. Fury, still alive, comments "he's not so ultimate". Supremus plans to turn the world into a "laboratory" where he'll use "genetic manipulation" to turn the entire human race into slaves to do his bidding. But Nick recognizes the caves Supremus is transmitting from as "The Caves Of Hercules" on Cape Spartel, from a Howlers mission during WW2. Dugan flies Fury there, and single-handedly Fury takes on Half-Man, an android, and a group of genetic mutates. With the help of Fatima, a woman seen at the riot in London, Nick manages to stop Supremus from setting off hidden caches of "zombie gas" in the US by remote control. Back at SHIELD HQ, she fills in the rest of the details, including that "Supremus" was really her half-brother.