The Beast confirms that Wolverine's healing factor has been totally wiped out by a Negative Zone virus and he is now completely mortal. This sends Wolvie into a mopey funk as he contemplates the possibility of his own death. Even a simple thing like cutting himself while shaving makes him nervous. While trying to deal with all of these new emotional issues, Fury tells him that the virus is still threatening to take over the world and has killed every meta-human who has control over viruses except for one. Her name is the Host and she is currently the prisoner of the Black Panther in Wakanda.