Bizarro-Lois gives birth to Bizarro-Jr. No. 1 who, while he thinks like a Bizarro looks like Superman when he was Super-Tot. When B-Jr. No. 1 becomes publicly known, Bizarro takes him out into space and stores him in an abandoned space capsule. The capsule crashes on Earth and Bizarro-Jr. No 1 is taken to the same Midvale Orphanage where Linda Lee (Supergirl) lives.; Linda Lee is assigned to watch the newly named baby Buster which lasts until B-Jr. No. 1 remembers the existence of his parents and flies off. Supergirl and Superman take Bizarro Jr. to the Fortress where they have him adopted by two of Superman's robots. During Jr.'s sleep period Supergirl's tries to do her chemistry homework and when her Heat Vision blows up her assignment she thinks she's turned "baby buster" into a Bizarro!; Bizarro-Jr. finds Lex's original Imperfect Duplicator while playing in the Fortress of Solitude and creates a Bizarro-Supergirl. Superman and Supergirl decide to return "Buster" to Bizarro world but Bizarro-Supergirl wants to keep him for her own. Bizarro spots his now-acceptable-looking child and and leads all the Bizarros into War against Earth.